Odd question for crossfire

I’m on mobile. My apologies.

So, I have 2 rx 560s, a dell motherboard (that i can not find documentation on for the life of me (yet appears to be crossfire compatible?)), and am running driver version 1.8.21.

My question is: Does crossfire have to be on in global settings for it to work?

I ask because I’ve been having trouble with crossfire recently so I figure I’ll turn it off in global settings. But when i did, the individual games still have crossfire options (the different profile options like AFR friendly and optimize 1 x 1) and I seemingly get better frame rates with the setting turned on rather than off and have none of the issues.

As a side note Radeon overly doesn’t seem to be working for me (I try the key combo (alt+r) and nothing happens) so I don’t know how else I can prove the second GPU is being used, the games just feel smoother.

Any help would be appreciated!