cant use certain tools (HELP ME!!)

I posted this here because it does have to to with modding tools,injectors,and my pc to.My problem is when i try to use certain tools like DTXconvert and Perx it will show up on my screen like its suppose to but when i click the key functions it wont do anything.For example when i use DTXconvert and click the [file] key in the upper left corner (example #1 in pic) it wont do anything,its there but not there.If i have a open file or program and move it past the open DTXconvert it will make a copy (examplke #2 in pic) of that certain part on the DTXconvert.If i try to exit the program by using the little red [X],or right click on the open program (example #3 in pic) in my lower toolbar it wont exit.If i just log off and back in i try to use the tools they wont show up at all.I restart my pc it will do as i first explained all over again.Now for the weird part,i tried running my pc in safe mode with networking and they work fine no problems.The programs are in sorta a limbo state.The picture shows but the program dont seem to fully load.I have ran malwarebytes and my AVG pro antivirus and deleted the so called (false positive) viruses from certain programs such Perx.I start over again with the same results as described above all over again.I hope i explained this the best way possible and someone may have a salution to help with.