Win 32 Help

Hey Guys, after about 1 or 2 hours of use on my computer doing anythiing with graphics, i get this Error that says Win32 Failed or Something, So i click dont send, and after that everything is all fucked up, like the cursor when you type, for me it just gos away, whenever i play a game the Graphics are all Fucked up, my theme go's away. Anyone Know what the Problem is? Everytime i get it, i just restart and it all good again, but then in 1 or 2 hours i get the Error again.